Search results for "Placenta Diseases"

showing 3 items of 3 documents

CD133 expression in placenta chorioangioma presenting as a giant asymptomatic mass

2021

Background: Placental chorioangioma is the most common benign non-trophoblastic neoplasm of the placenta. Its clinical relevance lies in the size of the tumor since larger masses cause pregnancy complications, including an unfavorable neonatal outcome. Case presentation: We report the case of a 34-year-old second gravida and nullipara at the 35th week of gestation, admitted to the gynecological department for antibiotic-resistant fever. The cardiotocography performed during hospitalization showed an abnormal fetal pattern. A 2250 g newborn was delivered by cesarean section. No complications were observed during childbirth and postpartum was insignificant. On gross inspection a white fleshy …

CD31Adultmedicine.medical_specialtyMedicine (General)Placenta Diseasesgiant asymptomatic maPlacentaCase Reportgiant asymptomatic massR5-920PregnancyPlacentamedicineChildbirthCD133 expression; Giant asymptomatic mass; Placental chorioangioma; Adult; Cesarean Section; Endothelial Cells; Female; Humans; Infant Newborn; Placenta; Pregnancy; Hemangioma; Placenta Diseases; Pregnancy Complications NeoplasticHumansClinical significanceCardiotocographyGiant asymptomatic massPregnancyFetusNeoplasticplacental chorioangiomamedicine.diagnostic_testObstetricsbusiness.industryCesarean SectionCD133 expression; Giant asymptomatic mass; Placental chorioangiomaEndothelial CellsInfantGeneral Medicinemedicine.diseaseNewbornPregnancy Complicationsmedicine.anatomical_structurePlacental chorioangiomaembryonic structuresGestationFemaleGiant asymptomatic mabusinessHemangiomaCD133 expression
researchProduct

Cell types infected in human cytomegalovirus placentitis identified by immunohistochemical double staining

1993

Chronic villitis is almost always present in intrauterine infection with human cytomegalovirus (HCMV). The inflammatory response to this virus has been described in detail. However, little is known about the types of placental cells that may be infected by HCMV and six cases of HCMV placentitis were thus investigated to identify the vulnerable cell types. Immunohistochemical double staining analyses were performed using antibodies to HCMV immediate early antigens and to specific cellular marker proteins. Fixed connective tissue cells could be demonstrated to be the predominantly infected cell type in each placental tissue. Endothelial cells and macrophages were also found to be infected in …

Human cytomegalovirusPathologymedicine.medical_specialtyPlacenta DiseasesTransplacental transmissionvirusesCongenital cytomegalovirus infectionCytomegalovirusConnective tissuePathology and Forensic MedicineAntigenPregnancymedicineHumansVimentinMacrophageEndotheliumPregnancy Complications InfectiousAntigens ViralMolecular BiologyCytopathic effectbiologyMacrophagesvirus diseasesCell BiologyGeneral Medicinemedicine.diseaseImmunohistochemistryVirologymedicine.anatomical_structureConnective TissueCytomegalovirus Infectionsbiology.proteinFemaleAntibodyVirchows Archiv A Pathological Anatomy and Histopathology
researchProduct

Imbalance of expression of bFGF and PK1 is associated with defective maturation and antenatal placental insufficiency.

2013

Abstract Objective Defective placental maturation is associated with restricted functional capacity and adverse perinatal fetal outcomes. The aim of the study was a comparative analysis of the role of mRNA expression of various angiogenic factors in placental maturation defects. Study design We examined the mRNA expression patterns of prokineticin 1 (PK1), its receptors (PKRs), basic-fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) in tissue from third-trimester placentae that exhibited delayed or accelerated villous maturation. Results The expression of PK1 and PKR2 was elevated in placental tissue exhibiting accelerated maturati…

Placental growth factorVascular Endothelial Growth Factor Amedicine.medical_specialtyPlacenta DiseasesReceptors Peptidemedicine.medical_treatmentPlacentaPregnancy Trimester ThirdPlacental insufficiencyBiologyPregnancy ProteinsReceptors G-Protein-CoupledGastrointestinal Hormoneschemistry.chemical_compoundPregnancyInternal medicinemedicineHumansReceptorPlacenta Growth FactorFetusGrowth factorObstetrics and Gynecologymedicine.diseaseProkineticinVascular endothelial growth factorEndocrinologyReproductive MedicinechemistryPIGFFemaleFibroblast Growth Factor 2Vascular Endothelial Growth Factor Endocrine-Gland-DerivedEuropean journal of obstetrics, gynecology, and reproductive biology
researchProduct